universal buffer

DNA/RNA Defend Pro™

  • inactivation of pathogens
  • stabilizes DNA
  • stabilizes RNA
  • stabilizes antigen
  • direct PCR compatible
  • lysis buffer
  • mucolytic
DNA/RNA Defend Pro™ is a nonionic detergent-based acidic medium for pathogen inactivation, stabilization of RNA/DNA/antigens, and lysis of biological samples. Compatible with extraction-free analytical procedures.

Viral RNA stability in saliva for at least 2 weeks at 37 °C

No Data Found

SARS-CoV-2 positive saliva sample stabilized in DNA/RNA Defend Pro under different conditions; Roche cobas Liat RT-qPCR result

No extraction required direct PCR compatible

No Data Found

Volume DNA/RNA Defend Pro in final RT-qPCR reaction

Direct RT-qPCR results of DNA/RNA Defend Pro compared to water control in four targets

flow cell
buffer

negative
control
100k
SARS-CoV-2 particles

DNA/RNA
Defend Pro*

negative
control
100k
SARS-CoV-2 particles

Quick antigen test compatible

* upon pH neutralization with NaOH prior to sample loading