universal buffer
DNA/RNA Defend Pro™
- inactivation of pathogens
- stabilizes DNA
- stabilizes RNA
- stabilizes antigen
- direct PCR compatible
- lysis buffer
- mucolytic
DNA/RNA Defend Pro™ is a nonionic detergent-based acidic medium for pathogen inactivation, stabilization of RNA/DNA/antigens, and lysis of biological samples. Compatible with extraction-free analytical procedures.
Viral RNA stability in saliva for at least 2 weeks at 37 °C
No Data Found
SARS-CoV-2 positive saliva sample stabilized in DNA/RNA Defend Pro under different conditions; Roche cobas Liat RT-qPCR result
No extraction required direct PCR compatible
No Data Found
Volume DNA/RNA Defend Pro in final RT-qPCR reaction
Direct RT-qPCR results of DNA/RNA Defend Pro compared to water control in four targets
flow cell
buffer
negative
control
100k
SARS-CoV-2 particles
DNA/RNA
Defend Pro*
negative
control
100k
SARS-CoV-2 particles
Quick antigen test compatible
* upon pH neutralization with NaOH prior to sample loading